About
I’m Dr Sophie Curio, an immunologist and bioinformatician working at the intersection of experimental research and computational analysis.
Discuss your project
My background in wet-lab immunology shapes the way I work with data. I want to understand the experimental setup, the strengths and limitations of the model, and the biological question before deciding which analysis will be useful.
Through Curio Science, I provide immunology consulting, bioinformatics analysis and research strategy support. I work directly with scientists and research teams, including teams without an internal bioinformatician.
A part-time position in Carlo Pulitano’s group alongside my consulting work. My work includes analysis of transcriptomic, metabolomic and lipidomic data in the context of liver transplants, alongside biological interpretation.
Founder & bioinformatics consultant. Sequencing analysis, reproducible workflows, biological interpretation and immunology research strategy.
Postdoctoral Research Fellow. Immune-cell mechanisms in cancer and inflammatory disease, computational workflows and collaborative research.
Doctoral research in immunology, investigating immune cells and receptors in inflammatory bowel disease and colorectal cancer.
Research internship involving experimental vaccine research.
The University of Sydney is a current research affiliation; Imperial, Harvard Medical School and UQ are previous research affiliations.
Cancer and inflammatory disease; NK cells, ILCs and T-cell biology; flow cytometry; confocal and intravital microscopy; molecular biology; primary immune cells, cell lines, organoids and mouse models.
Bulk and single-cell RNA-seq; chromatin accessibility; spatial transcriptomics; BCR/TCR repertoire analysis; flow cytometry data analysis; metabolomics and lipidomics; differential expression, pathway analysis and integration of complementary datasets.
Python and R; Scanpy, Seurat and ArchR; statistical analysis, visualisation and reproducible pipelines. Machine learning where it is appropriate to a defined research question.
PhD in Immunology and Master of Research, Imperial College London.
Bachelor of Science, University of Bonn.
Cao et al. · Co-author: Sophie Curio
Huang, Cao, Curio et al.
Curio & Belz
CellScope is my separate software project focused on reproducible workflows and reducing repetitive analysis work. Curio Science remains the home of my independent consulting, and I continue to take on projects.
I’m a glider pilot and flight instructor, and I enjoy ultrarunning. My interest in data also extends to Australian climate and gliding conditions, national parks and ECG modelling.
